A powerful combination of vitamins D3 and K2 for strong and healthy bones

From a young age, we are taught that for strong and healthy bones it is important to consume enough milk and dairy products, to be exposed to the sun and to eat fatty fish, crabs and seafood, some types of mushrooms and egg yolks, in order to synthesize a sufficient amount of vitamin D. But do you know that the health of your bones depends not only on calcium and vitamin D?

Although it is vitamin D₃ (cholecalciferol) known as a key factor in calcium absorption, scientific research indicates that vitamin K is required for its full effectiveness₂. These two vitamins work synergistically, and this connection can be crucial in preventing osteoporosis and reducing the risk of fractures, especially in old age.

How do vitamins D work?₃ and K₂?

Vitamin D₃ it helps the body to absorb calcium from food through the intestines and thereby increases the level of calcium in the blood. However, calcium itself, free and without interactions with proteins, can end up where it is not wanted, for example in blood vessels, which can contribute to the formation of calcifications and increase the risk of cardiovascular diseases.

That's where vitamin K comes in₂ (menaquinone), which activates special proteins dependent on vitamin K, such as osteocalcin and MGP (matrix Gla protein), which they direct calcium into bones and teeth, and prevent its deposition in soft tissues and blood vessels.

A review of numerous studies confirms that the combination of vitamins D and K is more effective than either vitamin alone. Animal and human studies show:

• better bone mineralization - supplementation D₃ and K₂ improves bone density and reduces the risk of fractures, especially in postmenopausal women,
• activation osteocalcin - vitamin D stimulates its production, while K₂ ensures its activity (carboxylation) and
• prevention vascular calcifications - the combination of these vitamins helps protect the arteries from calcium build-up, which can reduce the risk of heart attack and stroke.

Vitamin K exists in two forms: K₁ (mainly in green leafy vegetables) and K₂ (in fermented products like some cheeses). Vitamin K is particularly important for bone and heart health₂, especially in the form of MK-7, because it has greater bioavailability and a longer duration of action in the body. Although recommended doses for vitamin D3 are known (usually 800 to 2000 IU per day, depending on age and condition), the recommended daily dose of vitamin K₂ is 75 µg, although in studies the dose of 90 to 180 µg per day for MK-7 is most often used.

Vitamin D combination₃ and K₂ it can have far-reaching effects on bone health, but also on the cardiovascular system. It is important to emphasize that high doses of vitamin D without sufficient levels of vitamin K can even be harmful - due to the risk of excessive accumulation of calcium where it should not be.

Meet smart support for your bones, cartilage and muscles - in just one capsule a day

Almagea® MOTION SUPPORT+ is a new generation nutritional supplement formulated for those who want to maintain the vitality of movement in all phases of life. Contains a unique combination of clinically tested ingredients:

• UC-II®, which is a patented form of undenatured type II collagen. As little as 40 mg of UC-II® per day can have a comparable effect to traditional high doses of glucosamine and chondroitin.
• Vitamin K₂ and D₃ which contribute to the maintenance of normal bones.
• Vitamin D₃ which contributes to the maintenance of normal muscle function.
• Vitamin C, which contributes to the normal formation of collagen for the normal function of cartilage and bones.

Type II collagen is the key structural protein of cartilage that enables elasticity, firmness and smooth movement of joints. With age and load, its amount decreases, which can lead to cartilage wear and joint pain. Dietary supplements with undenatured type II collagen, such as UC-II®, help maintain cartilage health and improve mobility. The action of undenatured collagen type II (UC-II®) is supported by clinical studies, and in combination with vitamins K₂ and D₃, a synergistic effect is created that supports: joint mobility and flexibility, preservation of bone density, and cartilage and muscle health.

Almagea® MOTION SUPPORT+ is intended for:

• people with limited mobility and joint pain,
• elderly people to preserve bone mass and joint function,
• athletes and recreationists who want to protect cartilage and muscles in the long term and
• to everyone who wants to preventively preserve the health of the locomotor system.

Due to its unique formula, Almagea® MOTION SUPPORT+ provides comprehensive support for the health of joints, bones and muscles. Each ingredient works in a targeted and synergistic way: collagen restores the cartilage structure, vitamin C promotes its natural regeneration, while the combination of D₃ and K₂ ensures proper absorption and incorporation of calcium into bones. That's why Motion Support+ is a smart choice for anyone who wants to maintain mobility, reduce discomfort in the joints and long-term support the health of the locomotor system.

Literature:

• van Ballegooijen, A. J., Pilz, S., Tomaschitz, A., Grübler, M. R., & Verheyen, N. (2017). The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review. International journal of endocrinology, 2017, 7454376.
• Iwamoto, J., Takeda, T., & Ichimura, S. (2000). Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis. Journal of orthopedic science: official journal of the Japanese Orthopedic Association, 5(6), 546–551.
• Skalny, A. V., Aschner, M., Tsatsakis, A., Rocha, J. B. T., Santamaria, A., Spandidos, D. A., Martins, A. C., Lu, R., Korobeinikova, T. V., Chen, W., Chang, J. S., Chao, J. C. J., Li, C., & Tinkov, A. A. (2024). Role of vitamins beyond vitamin D₃ in bone health and osteoporosis (Review). International journal of molecular medicine, 53(1), 9.